Strawberry fields forever?

Strawberry fields forever?

On the basis of copious preclinical data supporting the preventive efficacy of small fruits such as berries and grapes, Chen and colleagues conducted a randomized (noncomparative) phase II trial evaluating two doses of strawberry powder (60 g/d or 30 g/d for six months) to prevent esophageal cancer in China (reported in this issue of the journal, beginning on page 41); 60 g/d reduced the histol...

Rosacea: The sTRawbeRRy Fields oF deRmaTology

Forever Young

Propagation of a species requires periodic cell renewal to avoid clonal senescence. Liu et al. (2010) now describe a new mechanism of cell renewal in budding yeast, in which damaged protein aggregates are transported out of the daughter buds along actin cables to preserve youthfulness.

Revision Forever!

Revision is a method to deal with non-monotonic processes. It has been used in theory of truth an an answer to semantic paradoxes as the liar, but the idea is universal and resurfaces in many areas of logic and applications of logic. In this survey, we describe the general idea in the framework of pointer semantics and point out that beyond the formal semantics given by Gupta and Belnap, the pr...

Bricolage forever!

According to constructivism, learning takes place by constructing cognitive structures. An experiment was carried out to uncover the mental models of experienced, but not professional, users of a word processor. The study shows that the mental models are superficial, and that bricolage (trial-and-error) is extensively used even though it is not viable for solving nontrivial problems. The conclu...